Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 9 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9NQS5 Q9NQS5 Q00765 GPR84 REEP5 human exp
Q9NQS5 Q9NQS5 Q16581 GPR84 C3AR1 human pred
Q9NQS5 Q9NQS5 Q9BY21 GPR84 GPR87 human pred
Q9NQS5 Q9NQS5 Q15391 GPR84 P2RY14 human pred
Q9NQS5 Q9NQS5 O14593 GPR84 RFXANK human ortho
Q9NQS5 Q9NQS5 Q6ZMG9 GPR84 CERS6 human exp
Q9NQS5 Q9NQS5 Q8WVP7 GPR84 LMBR1 human exp
Q9NQS5 Q9NQS5 Q6ZN17 GPR84 LIN28B human ortho
Q9NQS5 Q9NQS5 Q8IYL9 GPR84 GPR65 human pred

Return to Output Options

Return to top

Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.