Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:


Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues




Results exceeding 3000 interactions will be returned as a downloadable file
  


Results

Retrieved 66 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9NTG7 Q9NTG7 P10809 SIRT3 HSPD1 human exp
Q9NTG7 Q9NTG7 O43524 SIRT3 FOXO3 human exp,pred
Q9NTG7 Q9NTG7 Q9UNY4 SIRT3 TTF2 human exp
Q9NTG7 Q9NTG7 O75746 SIRT3 SLC25A12 human pred
Q9NTG7 Q9NTG7 Q9NY33 SIRT3 DPP3 human pred
Q9NTG7 Q9NTG7 Q96DR7 SIRT3 ARHGEF26 human exp
Q9NTG7 Q9NTG7 P12956 SIRT3 XRCC6 human exp,pred
Q9NTG7 Q9NTG7 Q9UNM6 SIRT3 PSMD13 human pred
Q9NTG7 Q9NTG7 Q9NXA8 SIRT3 SIRT5 human exp,pred
Q9NTG7 Q9NTG7 P40926 SIRT3 MDH2 human pred
Q9NTG7 Q9NTG7 O95248 SIRT3 SBF1 human exp
Q9NTG7 Q9NTG7 P14625 SIRT3 HSP90B1 human exp
Q9NTG7 Q9NTG7 O60313 SIRT3 OPA1 human exp,ortho
Q9NTG7 Q9NTG7 O00429 SIRT3 DNM1L human exp,pred
Q9NTG7 Q9NTG7 P10515 SIRT3 DLAT human exp
Q9NTG7 Q9NTG7 Q6FI81 SIRT3 CIAPIN1 human pred
Q9NTG7 Q9NTG7 Q9UPY3 SIRT3 DICER1 human pred
Q9NTG7 Q9NTG7 Q9Y5L4 SIRT3 TIMM13 human pred
Q9NTG7 Q9NTG7 Q15021 SIRT3 NCAPD2 human exp
Q9NTG7 Q9NTG7 Q04206 SIRT3 RELA human pred
Q9NTG7 Q9NTG7 Q13884 SIRT3 SNTB1 human exp
Q9NTG7 Q9NTG7 P50542 SIRT3 PEX5 human exp,pred
Q9NTG7 Q9NTG7 Q8IWA4 SIRT3 MFN1 human pred
Q9NTG7 Q9NTG7 Q9NX47 SIRT3 MARCH5 human pred
Q9NTG7 Q9NTG7 P07919 SIRT3 UQCRH human exp
Q9NTG7 Q9NTG7 O60729 SIRT3 CDC14B human pred
Q9NTG7 Q9NTG7 Q9BX40 SIRT3 LSM14B human exp
Q9NTG7 Q9NTG7 Q00169 SIRT3 PITPNA human exp
Q9NTG7 Q9NTG7 P34931 SIRT3 HSPA1L human exp
Q9NTG7 Q9NTG7 Q13163 SIRT3 MAP2K5 human exp
Q9NTG7 Q9NTG7 Q9NS18 SIRT3 GLRX2 human pred
Q9NTG7 Q9NTG7 Q8IXJ6 SIRT3 SIRT2 human pred
Q9NTG7 Q9NTG7 Q8N3K9 SIRT3 CMYA5 human exp
Q9NTG7 Q9NTG7 Q14061 SIRT3 COX17 human pred
Q9NTG7 Q9NTG7 P05091 SIRT3 ALDH2 human exp,ortho
Q9NTG7 Q9NTG7 Q9UQL6 SIRT3 HDAC5 human pred
Q9NTG7 Q9NTG7 Q96TA2 SIRT3 YME1L1 human pred
Q9NTG7 Q9NTG7 Q16795 SIRT3 NDUFA9 human exp,ortho
Q9NTG7 Q9NTG7 P38646 SIRT3 HSPA9 human exp
Q9NTG7 Q9NTG7 Q9NRC8 SIRT3 SIRT7 human pred
Q9NTG7 Q9NTG7 P06576 SIRT3 ATP5B human exp
Q9NTG7 Q9NTG7 Q14565 SIRT3 DMC1 human exp
Q9NTG7 Q9NTG7 Q5UIP0 SIRT3 RIF1 human exp
Q9NTG7 Q9NTG7 Q8N4Q1 SIRT3 CHCHD4 human pred
Q9NTG7 Q9NTG7 Q8N6T7 SIRT3 SIRT6 human pred
Q9NTG7 Q9NTG7 O14976 SIRT3 GAK human pred
Q9NTG7 Q9NTG7 O75880 SIRT3 SCO1 human pred
Q9NTG7 Q9NTG7 P34932 SIRT3 HSPA4 human exp
Q9NTG7 Q9NTG7 P09543 SIRT3 CNP human exp
Q9NTG7 Q9NTG7 Q96EB6 SIRT3 SIRT1 human pred
Q9NTG7 Q9NTG7 P62072 SIRT3 TIMM10 human pred
Q9NTG7 Q9NTG7 P28799 SIRT3 GRN human exp
Q9NTG7 Q9NTG7 Q9NUB1 SIRT3 ACSS1 human pred
Q9NTG7 Q9NTG7 Q75T13 SIRT3 PGAP1 human exp
Q9NTG7 Q9NTG7 O60701 SIRT3 UGDH human exp
Q9NTG7 Q9NTG7 Q13309 SIRT3 SKP2 human exp
Q9NTG7 Q9NTG7 P51687 SIRT3 SUOX human pred
Q9NTG7 Q9NTG7 P11021 SIRT3 HSPA5 human exp
Q9NTG7 Q9NTG7 Q9Y6N1 SIRT3 COX11 human pred
Q9NTG7 Q9NTG7 P25705 SIRT3 ATP5A1 human exp
Q9NTG7 Q9NTG7 Q06587 SIRT3 RING1 human pred
Q9NTG7 Q9NTG7 O95714 SIRT3 HERC2 human exp
Q9NTG7 Q9NTG7 Q9Y5J7 SIRT3 TIMM9 human pred
Q9NTG7 Q9NTG7 Q9Y6E7 SIRT3 - human exp,pred
Q9NTG7 Q9NTG7 O95299 SIRT3 NDUFA10 human exp
Q9NTG7 Q9NTG7 Q9H300 SIRT3 PARL human pred

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.