Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 9 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9UGH3 Q9UGH3 O15120 SLC23A2 AGPAT2 human exp
Q9UGH3 Q9UGH3 O14745 SLC23A2 SLC9A3R1 human exp
Q9UGH3 Q9UGH3 P11166 SLC23A2 SLC2A1 human pred
Q9UGH3 Q9UGH3 Q16671 SLC23A2 AMHR2 human pred
Q9UGH3 Q9UGH3 Q5JR59 SLC23A2 MTUS2 human pred
Q9UGH3 Q9UGH3 P46934 SLC23A2 NEDD4 human exp
Q9UGH3 Q9UGH3 O00141 SLC23A2 SGK1 human pred
Q9UGH3 Q9UGH3 P15313 SLC23A2 ATP6V1B1 human exp
Q9UGH3 Q9UGH3 Q9GZY4 SLC23A2 COA1 human exp

Return to Output Options

Return to top

Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.