Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 11 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9UJJ7 Q9UJJ7 Q96PZ0 RPUSD1 PUS7 human pred
Q9UJJ7 Q9UJJ7 P27695 RPUSD1 APEX1 human ortho
Q9UJJ7 Q9UJJ7 Q96S55 RPUSD1 WRNIP1 human ortho
Q9UJJ7 Q9UJJ7 Q8IZ73 RPUSD1 RPUSD2 human pred
Q9UJJ7 Q9UJJ7 O95900 RPUSD1 TRUB2 human pred
Q9UJJ7 Q9UJJ7 P26196 RPUSD1 DDX6 human ortho
Q9UJJ7 Q9UJJ7 Q9Y285 RPUSD1 FARSA human ortho
Q9UJJ7 Q9UJJ7 Q9GZT8 RPUSD1 NIF3L1 human ortho
Q9UJJ7 Q9UJJ7 Q8WWH5 RPUSD1 TRUB1 human pred
Q9UJJ7 Q9UJJ7 Q9NQ94 RPUSD1 A1CF human pred
Q9UJJ7 Q9UJJ7 Q92949 RPUSD1 FOXJ1 human exp

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.