Find interaction partners supported by:

Experimental evidence
Orthologous interaction evidence
Computational predictions

Retrieve only interactions among query proteins
Include interactions among partners of query proteins

1. Enter protein, gene, or dataset IDs:

Maximum number of IDs: 100
Accepted IDs: Symbol (e.g., TP53), UniProt (e.g., P04637), Entrez Gene (e.g., 7157)

Options for searching across species:

Search using orthologs of your proteins
Return only interactions conserved across all selected species

2. Select species:

Options for searching across tissues:

Return only interactions present in all selected tissues
Required evidence: gene OR protein expression
Required evidence: gene AND protein expression

3. Select tissues:

Some tissues are not available for some species

Output Options

Information to include in output table:

Source information: detection methods, PubMed IDs, reporting databases
Tissue information: presence/absence of interactions in selected tissues

Results exceeding 3000 interactions will be returned as a downloadable file


Retrieved 11 PPIs for 1 ID

Query ID Query UniProt Partner UniProt Query Symbol Partner Symbol Species Evidence Type
Q9UN79 Q9UN79 P35711 SOX13 SOX5 human exp
Q9UN79 Q9UN79 Q6P2H3 SOX13 CEP85 human exp
Q9UN79 Q9UN79 O14980 SOX13 XPO1 human exp
Q9UN79 Q9UN79 Q14258 SOX13 TRIM25 human exp
Q9UN79 Q9UN79 Q96MU7 SOX13 YTHDC1 human exp
Q9UN79 Q9UN79 O96018 SOX13 APBA3 human exp
Q9UN79 Q9UN79 P56545 SOX13 CTBP2 human exp
Q9UN79 Q9UN79 Q5QGZ9 SOX13 CLEC12A human exp
Q9UN79 Q9UN79 O15105 SOX13 SMAD7 human exp
Q9UN79 Q9UN79 Q16849 SOX13 PTPRN human pred
Q9UN79 Q9UN79 Q9UN79 SOX13 SOX13 human exp

Return to Output Options

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Citing IID

Kotlyar, M., Pastrello, C., Sheahan, N., Jurisica, I. Integrated Interactions Database: Tissue-specific view of the human and model organism interactomes, Nucleic Acids Res, 44(D1): D536-41, 2016.